What does the Registry do?
- The Registry creates a repository of clinical and biologic data for ovarian and testicular stromal tumors to facilitate current and future research
- The Registry provides expert pathologic assessment establishing the diagnosis of ovarian and testicular stromal tumors and similar tumors and provide histopathologic details for each patient
- The Registry determines the prevalence of DICER1 germline mutations in patients with ovarian and testicular stromal tumors
- The Registry determines the DICER1 immunohistochemical expression and miRNA expression profiles of gonadal stromal tumors with and without germline DICER1 mutations.
The Registry will collect and analyze case-by-case data on gonadal stromal tumors.
Cases are identified:
1. By referrals from clinicians or pathologists.
2. By families initiating contact with the Registery for information.
3. By Registry requests to authors of published cases to share further details.
4. From existing tumor registries or tumor banks such as CCRN (Childhood Cancer Registry Network, etc.) when permission for future contact is obtained.